OraVital® System Research

The patent pending OraVital System is evidence-based. Our philosophy is directed by research and science. The basis of the scientific precepts of OraVital® evolved from the 15 years of research and successful clinical evidence in the Fresh Breath Clinic operated by Anne Bosy and Dr. Julian Geller, DDS, as well as the extensive research of the late Dr. Walter Loesche. one of the world’s authorities on caries and periodontal disease, and a former Marcus L. Ward Professor of Dentistry in the Department of Biologic Materials Sciences at the University of Michigan School of Dentistry.

“Treatment of Oral Malodor and Periodontal Disease Using an Antibiotic Rinse”

The purpose of this study, originally published in the Academy of General Dentistry publication, General Dentistry was to determine the effectiveness of an antibiotic rinse preparation, containing metronidazole and nystatin, in decreasing oral malodor and periodontal disease for individuals whose chief complaint was halitosis.

  • There is a considerable advantage to the use of topical antibiotic rinses.
  • A topical application, in the form of a rinse with tiny particles of antibiotic, will coat all oral tissues, as well as the tonsillar areas, achieving an overall decrease in halitosis and periodontal disease markers without the risk of the systemic effects of an oral antibiotic.

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“Primary Prevention of Periodontitis: Managing Gingivitis” 

The OraVital System is a strong proponent of the superior efficacy of interdental devices compared to dental floss for controlling plaque and biofilm. This study is a meta-analysis of the efficacy of the main types of plaque control for preventing periodontitis, including self-administered inter-dental mechanical plaque control.

  • There is moderate evidence to suggest that the adjunctive use of interdental brushes provides higher levels of plaque removal than manual tooth brushing alone.
  • Other interproximal cleaning devices such as flossing show very inconsistent/weak evidence for an adjunctive effect, due to a lack of efficacy.

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“Using an Antibiotic Rinse System: An Adjunct in the Treatment of Periodontal Disease”

This study published in Oral Health Magazine stated that the structure and behavior of biofilm is what makes treatment of these periodontal infections difficult. It has been found that the minimal inhibitory concentration dose for antibiotics and antimicrobials for bacteria in biofilm may be 20 to 200 times higher than required for free floating or plankton bacteria. The study examined oral antibiotics as a possible solution for controlling these persistent bacteria. Here are the findings:

  • The results provided strong evidence that an antibiotic mouth rinse containing metronidazole and nystatin is effective in the treatment of periodontitis.
  • Gingival tissues were healthier, with fewer bleeding points and a decrease in periodontal pocket depth.
  • This system fits within the guidelines of the American Academy of Periodontology.
  • The results indicate that a rinse system provides a beneficial adjunct in the treatment of periodontal disease.

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